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Lefkovits Ivan

Prof., Dr.
Born January 21, 1937 in Prešov

  • Honorary member of Learned Society since 2000

Educational and professional preparation:

  • 1956, graduate, secondary school, Prague;
  • 1956-1961, Institute of Chemical Technology, Prague;
  • 1979, Assistant Professor, Philipps-Universitaet, Marburg (FRG);
  • 1989, Professor of immunology Philipps-Universitaet

Employment and academic positions:

  • 1962–1964, post graduate student, Institute of Microbiology, Czechoslovak Academy of Sciences, Prague;
  • 1965–1967, Laboratorio Internationale di Genetica e Biofisica, Naples, Italy;
  • 1967–1969, Paul-Ehrlich Institut, Frankfurt (FRG);
  • 1969–2001, Basel Institute for Immunology, Basel (Switzerland);
  • 2002-present, Research Department, University Clinics, Basel;
  • 1977–2001, lectures in immunology, Marburg; Sabbaticals:
  • 1997, visiting professor, Sir William Dunn School of Pathology, Oxford, (UK);
  • 1999 visiting professor at Hopital Necker, Paris (France);
  • 2002, visiting professor, Erasmus University, Rotterdam (Netherlands);
  • 2004, visiting scientist at Trudeau Institute, Saranac Lake, New York (USA)

Membership and positions in international organizations and societies:

  • Advisory Board, University of Latvia Biomedical Research Study Centre (BMC), Riga.
  • 1993-2001, Member, Assembly, Academy of Sciences of the Czech Republic (AS CR)
  • Member, Educational Committee, International Union of Immunological Societies (IUIS)
  • 1992-1995, Chairman, Central European Summer School of Immunology
  • Member, International Cell Research Organization (ICRO)
  • Proteome Center for Study of Intracellular Parasitism, Hradec Králové
  • British Society for Immunology (UK)
  • Deutsche Gesellschaft für Immunologie (FRG)
  • Schweizerische Gesellschaft für Immunologie (CH)
  • Swiss Proteomic Society (CH)
  • Honorary Member, Indian Immunology Society
  • Honorary Member, Czechoslovak Immunological Society
  • Honorary Member, Czechoslovak Microbiological Society

Notable awards:

  • 1969, Named permanent member of Basel Institute for Immunology
  • 1992, Golden Reiman Medal (Reiman Society, Prešov)
  • 1995, G.J. Mendel Honorary Medal, AS CR

Selected publications:

  • I. Lefkovits: Induction of antibody-forming cell clones in microcultures. Eur. J. Immuol. 2, 360-365, 1972
  • I. Lefkovits: Precommitment in the immune system. Current Topics in Microbiol. And Immunol. 65, 21-58, 1974
  • I. Lefkovits, J. Quintans, A. Munro, H. Waldmann: T-Cell dependent mediator and B-cell clones. Immunology 28, 1149-1154, 1975
  • I. Lefkovits, P. Young, L. Kuhn, J. Kettman, A. Gemmell, S. Tollaksen, L. Anderson, N. Anderson: Use of large scale two-dimensional ISODALT gel electrophoresis system in immunology. In: Immunological Methods, Vol. 3 (I. Lefkovits and B. Pernis, Eds.) pp. 163-185, Academic Press, New York, 1985
  • I. Lefkovits: Self and non-self discrimination by „restriction proteases“. Proc. Natl. Acad. Sci. U.S.A. 83, 3437-3438, 1986
  • I. Lefkovits, L. Kuhn, 0. Valiron, A. Merle, J. Kettman: Toward an objective classification of cells in the immune system. Proc. Natl. Acad. Sci. 85, 3565-3569, 1988
  • C. Coleclough, L. Kuhn, I. Lefkovits: Regulation of messenger RNA abundance in activated T lymphocytes: Identification of mRNA species affected by the inhibition of protein synthesis. Proc. Natl. Acad. Sci. USA 87, 1753-1757, 1990
  • I. Lefkovits, J. Kettman and C. Coleclough: A strategy for founding a global lymphocyte proteinpaedia and gene catalogue. Immunol. Today 11, 157-162, 1990
  • I. Lefkovits and H. Waldmann: Limiting dilution analysis of cells in the immune system (second edition), 285 pages, Oxford University Press, 1999
  • I. Lefkovits: Functional and structural proteomics: a critical appraisal. J. Chromat. B, 787, 1-10, 2003
  • H. R. Zerkowski, T. Grussenmeyer, P. Matt, M. Grapow. S. Engelhardt and I. Lefkovits: Proteomics Strategies in Cardiovascular Research. J. Proteome Res. 3, 200-208, 2004