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Damborský Jiří

Prof., Mgr., Ph.D.
Born September 29, 1969 in Brno

  • Protein and metabolic engineering
  • Member of Learned Society since 2013

Educational and professional preparation

  • 2011, Sabbatical Stay, Department of Biochemistry, University of Washington, Seattle, USA
  • 2011, Prof., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 2004, EMBO YIP Networking, Bioinformatics Group, International Institute of Molecular and Cell Biology, Warsaw, PL
  • 2004, Doc., Biochemistry, Faculty of Science, Masaryk University, Brno, CZ
  • 1997, Ph.D., Microbiology, Masaryk University, Brno, CZ
  • 1997, Scholarship of the Swedish Institute, Research Group for Chemometrics, Umea University, Umea, S
  • 1997, Department of Civil and Environmental Engineering, The University of Michigan, Ann Arbor, USA
  • 1996, FEMS Fellowship, Department of Biochemistry and Department of Biophysics, University of Groningen,Groningen, NL
  • 1994, UNESCO Fellowship, International Institute for Biotechnology, University of Kent at Canterbury, Canterbury, UK
  • 1994, USIA Exchange Program Grant, Center for Environmental Biotechnology, University of Tennessee, Knoxville, USA
  • 1993, TEMPUS Student Mobility Project, Research Institute of Toxicology, University of Utrecht, Utrecht, NL
  • 1993, MSc., Microbiology, Masaryk University, Brno, CZ

Employment and academic positions

  • 2011-now, International Centre for Clinical Research, Brno, CZ
  • 2009-now, Josef Loschmidt Chair, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, CZ
  • 2007-2009, Josef Loschmidt Chair, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, CZ
  • 2003-2007, Josef Loschmidt Chair, Faculty of Science, Masaryk University, Brno, CZ
  • 1996-2003, National Centre for Biomolecular, Faculty of Science, Masaryk University, Brno, CZ

Membership and positions in international organizations and societies

  • 2009-now, Microbial Biotechnology, Member of Editorial Board, Blackwell Publishing, USA
  • 2008-now, Current Opinion in Biotechnology, Member of Editorial Board, Elsevier, NL
  • 2005-now, Biotechnology Journal, Member of Editorial Board, Wiley-VCH, D
  • 2003-2008, Central European Journal of Chemistry, Editor, Biological Chemistry and Biochemistry, Central European Science Journals, PL
  • 2003-2008, FEMS Microbiology Reviews, Editor, Federation of European Microbiological Societies, Elsevier, NL
  • 2001-2003, Environmental Toxicology and Chemistry, Member of Editorial Board, SETAC Press, USA

Notable awards

  • 2003, European Molecular Biology Organization and Howard Hughes Medical Institute, EMBO/HHMI Scientist
  • 2003, Award of the Czech Chemical Society, Alfred Bader Prize for Bioorganic Chemistry
  • 1998, Award of the Czech Society for Biochemistry and Molecular Biology, BIOTECH
  • 1997, Award of the Czechoslovak Microbiological Society, Young Czech and Slovak Microbiologist of the Year
  • 1993, Award of the Dean of the Faculty of Science, Masaryk University

Selected publications

  • Damborský, J., Brezovský, J., 2014: Computational Methods for Designing and Engineering Biocatalysts. Current Opinion of Chemical Biology 19: 8-16.
  • Gora, A., Brezovský, J., Damborský, J., 2013: Gates of Enzymes. Chemical Reviews 113: 5871–5923.
  • Koudeláková, T., Chaloupková, R., Brezovský, J., Prokop, Z., Pavlová, M., Hessler, M., Khabiri, M., Ettrich, R., Bornscheuer, U.T., Damborský, J., 2013: Engineering Protein Resistance to Organic Co-solvent and Elevated Temperature by Access Tunnel Modification. Angewandte Chemie International Edition 52: 1959-1963.
  • Martins dos Santos, V.A.P., Damborský, J., 2010: Systems Biology at Work. Current Opinion in Biotechnology 21: 498-501.
  • Prokop, Z., Sato, Y., Brezovský, J., Mozga, T., Chaloupková, R., Koudeláková, T., Jeřábek, P., Štěpánková, V., Natsume, R., van Leeuwen, J.G.E., Janssen, D.B., Florián, J., Nagata, Y., Senda, T., Damborský, J., 2010: Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering. Angewandte Chemie 49: 6111-6115.
  • Damborský, J., Brezovský, J., 2009: Computational Tools for Designing and Engineering Biocatalysts. Current Opinion in Chemical Biology 13: 26-34.
  • Jesenská, A., Sýkora, J., Olżyńska, A., Brezovský, J., Zdráhal, Z., Damborský, J., Hof, M., 2009: Nanosecond Time-Dependent Stokes Shift at the Tunnel Mouth of Haloalkane Dehalogenases. Journal of the American Chemical Society 131: 494-501.
  • Pavelka, A., Chovancová, E., Damborský, J., 2009: HotSpot Wizard: A Web Server for Identification of Hot Spots in Protein Engineering. Nucleic Acids Research 37: W376–W383.
  • Pavlová, M., Klvaňa, M., Chaloupková, R., Banáš, P., Otyepka, M., Wade, R., Nagata, Y., Damborský, J., 2009: Redesigning Dehalogenase Access Tunnels as a Strategy for Degrading an Anthropogenic Substrate. Nature Chemical Biology 5: 727 - 733.