Calendar

20. – 21.05.2019

XXV AGM

20. 5 Karolinum – all day, evening: Vila Lanna21. 5. CAS building, all day

Kopeček Jindřich

Distinguished Professor, D.Sc.
Born January 27, 1940 in Strakonice

  • Chemist
  • Member of Learned Society since 1998
Institution:
  • Department of Pharmaceutics and Pharmaceutical Chemistry, Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112, USA

Educational and professional preparation:

  • 1990, D.Sc., chemistry, Czechoslovak Academy of Sciences (CSAS);
  • 1967-1968, Post-doctoral Fellow, National Research Council of Canada, Ottawa;
  • 1965, Ph.D., macromolecular chemistry, Institute of Macromolecular Chemistry (IMC) CSAS;
  • 1961, M.S., macromolecular chemistry, Institute of Chemical Technology, Prague

Employment and academic positions:

  • 2002-present, Distinguished Professor of Pharmaceutics and Pharmaceutical Chemistry, Distinguished Professor of Bioengineering, University of Utah;
  • 1999-2004, Chairman, Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah;
  • 1989-2002, Professor of Pharmaceutics and Pharmaceutical Chemistry, Professor of Bioengineering, University of Utah;
  • 1986-present, Co-Director, Center for Controlled Chemical Delivery, University of Utah;
  • 1983-2000, Visiting Professor, Université Paris-Nord;
  • 1986-1988, University of Utah; 1999, Tokyo Women’s Medical University;
  • 1972-1988, Head, Laboratory, Institute of Macromolecular Chemistry, CSAS;
  • 1965-1972, Scientific Officer, Institute of Macromolecular Chemistry, CSAS

Membership and positions in international organizations and societies:

  • Controlled Release Society: President 1995-1996; Vice-President 1993-1994; member, Board of Governors 1988-1991; Chairman, Nagai Award Committee, 2002-present.
  • Member, Biomaterials Society
  • Member, American Association for the Advancement of Science
  • Member, American Association for Cancer Research
  • Member, American Association of Pharmaceutical Scientists
  • Member, Society for Molecular Recognition
  • Member, American Society for Photobiology

Notable awards:

  • 2004, Chair, Gordon Research Conference on Drug Carriers in Medicine and Biology
  • 2003-present,, Chair, National Institutes of Health, Biomaterials and Biointerfaces Study Section
  • 2003, Heyrovský Medal for merit in the chemical sciences, Academy of Sciences of the Czech Republic
  • 2003, AAPS PharmSci and AAPS PharmSciTech Outstanding Use of Technology, Award for best publication in AAPS PharmSci, American Association of Pharmaceutical Scientists
  • 2001, Paul Dawson Biotechnology Award, American Association of Colleges of Pharmacy
  • 2000, Millennial Pharmaceutical Scientist, Millennial World Congress of Pharmaceutical Sciences
  • 1999, Fellow of Biomaterials Science and Engineering, International Union of Societies of Biomaterials Science and Engineering
  • 1999, J. Heller Award for best publication in Journal of Controlled Release
  • 1999, Founders Award, Controlled Release Society
  • 1995, Clemson Award (for Basic Research, Society for Biomaterials)
  • 1995, Fellow, American Institute for Medical and Biological Engineering
  • 1994, Fellow, American Association of Pharmaceutical Scientists
  • 1993, Distinguished Research Award, University of Utah
  • 1992, Program Chairman, 19th International Symposium on Controlled Release of Bioactive Materials, Orlando, Florida
  • 1990, Barre’s Lecture, Université de Montreal

Member, Editorial Boards:

  • 1973-1996, Polymers in Medicine (Wroclaw)
  • 1986-1998, New Polymeric Materials
  • 1992-1998, Polymer Gels and Networks
  • 1980-present, Biomaterials
  • 1981-present, Critical Reviews in Therapeutic Drug Carrier Systems
  • 1984-present, Journal of Controlled Release
  • 1986-present, Journal of Bioactive and Compatible Polymers
  • 1987-present, Journal of Biomaterials Science
  • 1991-present, Drug Delivery
  • 1992-present, European Journal of Pharmaceutics and Biopharmaceutics
  • 1993-present, Bioconjugate Chemistry
  • 1995-present, Pharmaceutical Research
  • 1999-present, The AAPS Journal (formerly AAPS PharmSci)
  • 2001-present, Advanced Drug Delivery Reviews
  • 2002-present, Journal of Drug Delivery Science and Technology (formerly STP Pharma Sciences)
  • 2002-present, European Journal of Pharmaceutical Sciences

Research interests:

  • Biorecognition of Macromolecules
  • Bioconjugate Chemistry
  • Drug Delivery Systems
  • Genetically Engineered Materials
  • Self-Assembly of Macromolecules

Notable publications:

  • N. Nishiyama, A. Nori, A. Malugin, Y. Kasuya, P. Kopeckova, J. Kopecek: Free and N-(2-Hydroxypropyl)methacrylamide (HPMA) Copolymer-bound Geldanamycin Derivative Induce Different Stress Responses in A2780 Human Ovarian Carcinoma Cells. Cancer Res. 63, 7876-7882 (2003)
  • A. Nori, K.D. Jensen, M. Tijerina, P. Kopeckova, J. Kopecek, Tat Conjugated Synthetic Macromolecules Facilitate Cytoplasmic Drug Delivery to Human Ovarian Carcinoma Cells. Bioconjugate Chem. 14, 44-50 (2003)
  • J. Kopecek, Smart and Genetically Engineered Biomaterials and Drug Delivery Systems, Eur. J. Pharm. Sci. 20, 1-16 (2003)
  • D. Wang, M. Pechar, W. Li, P. Kopeckova, D. Brömme, J. Kopecek: Inhibition of Cathepsin K with Lysosomotropic Macromolecular Inhibitors, Biochemistry 41, 8849-8859 (2002)
  • A. Tang, J. Kopecek, Presentations of Epitopes on Peptide Scaffolds and Selection of Lymphoma-Targeting Moieties Based on Epitope Recognition. Biomacromolecules 3, 421-431 (2002)
  • J.-G. Shiah, M. Dvorak, P. Kopeckova, Y. Sun, C. M. Peterson, J. Kopecek: Biodistribution and Antitumor Efficacy of Long-Circulating N-(2-Hyd-roxy-propyl)methacrylamide Copolymer-Doxorubicin Conjugates in Nude Mice,
    Eur. J. Cancer
    37, 131-139 (2001)
  • T. Minko, P. Kopeckova, J. Kopecek: Efficacy of Chemotherapeutic Action of HPMA Copolymer-Bound Doxorubicin in a Solid Tumor Model of Ovarian Carcinoma.
    Int. J. Cancer, 86, 108-117 (2000)
  • J.-G. Shiah, Y. Sun, C. M. Peterson, R. C. Straight, J. Kopecek: Antitumor Activity of HPMA Copolymer-Meso Chlorin e6 and Adriamycin Conjugates in Combination Treatments. Clin. Cancer Res. 6, 1008-1015 (2000)
  • Z.-R. Lu, P. Kopeckova, J. Kopecek: Polymerizable Fab’ Antibody Fragments for Targeting of Anticancer Drugs. Nature Biotechnology 17, 1101-1104 (1999)
  • C. Wang, R. J. Stewart, J. Kopecek: Hybrid Hydrogels Assembled from Synthetic Polymers and Coiled-Coil Protein Domains. Nature 397, 417-420 (1999)

visit the website »

Back to the list of articles

News

27.03.19

International Society on General Relativity and Gravitation elects prof. Jiří Bičák a Fellow

The International Society on General Relativity and Gravitation was founded in 1971 with the objective of promoting the study of general relativity and gravitation, and its application in astrophysics and cosmology. It currently has over 1500 registered individual members, alongside a number of national companies.

14.03.19

Invitation to a Learned Society plenary lecture open to the public

The Learned Society warmly invites you to a lecture by Prof. RNDr. Martin Loebl, CSc. (Charles University Faculty of Mathematics and Physics): “Paths”
The lecture is to be held on 23 April 2019 from 4:00 pm in rooms 205 and 206 of the Czech Academy of Sciences building, Národní 3, Prague 1.

10.03.19

Declaration of support for the student climate strikes

Declaration by the below signed members of the Learned Society and other scientists giving their support for the 15 March 2019 student climate strikes
Declaration (PDF, 36 kB)