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Šponer Jiří

Prof., RNDr., DrSc.
Born March 2, 1964 in Brno

  • Molecular Biophysics and Computational Chemistry
  • Member of Learned Society since 2006

Educational and professional preparation:

  • 1987, Master degree (RNDr), Physics, Faculty of Science, Masaryk University, Brno 
  • 1992, CSc. (eq. PhD), Biophysics, Faculty of Science, Masaryk University, Brno 
  • 2001, DrSc. (Doctor of Science), Biophysics/Molecular Biology, Academy of Sciences of the Czech Republic

Employment and academic positions: 

  • 1988–1989, Scholarship, Masaryk University, Faculty of Science, Masaryk University, Brno (including one-year army service).
  • 1989–1992, Postgraduate student, Faculty of Medicine, Masaryk University, Brno.  
  • 1992, Scholarship, assistant professor, Masaryk University, Faculty of Science, Brno.
  • 1993, Junior researcher, Institute of Biohysics, Academy of Sciences of the Czech Republic, Brno 
  • 1994–2003, Researcher and Senior Research, J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague (part time 2001–2003).  
  • 2001-present: Senior Researcher and Head of Laboratory of Structure and Dynamics of Nucleic Acids, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno. 
  • 2004-present: (part time) Senior researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.

Membership in selected domestic scientific bodies:

  • Member of the Scientific Council of the Institute of Biophysics, AS CR, Brno. Since 2001

Notable awards:

  • 1999, Prize od the Learned Society of the Czech Republic for junior scientists
  • 2000, Prize of the Ministry of Education of the Czech Republic

Selected publications:

  • Šponer J., Hobza P.: Nonplanar geometries of DNA bases. Second order Moller-Plesset study. J. Phys. Chem. 98, 1994, 3161-3164.
  • Šponer J., Leszczynski J., Hobza P.: Structures and energies of hydrogen-bonded DNA base pairs. A nonempirical study with inclusion of electron correlation. J. Phys. Chem. 100, 1996, 1965-1974.
  • Šponer J., Leszczynski, J., Hobza P.: On the nature of nucleic acid base stacking. Nonempirical ab initio and empirical potential characterization of 10 stacked base pairs. Comparison of stacked and H-bonded base pairs. J. Phys. Chem. 100, 1996, 5590-5596.
  • Špacková N., Berger I., Šponer J.: Nanosecond molecular dynamics simulations of parallel and antiparallel guanine quadruplex molecules. J. Am. Chem. Soc. 121, 1999, 5519-5534.
  • Hobza P., Šponer J.: Structure, energetics, and dynamics of the nucleic acid base pairs: Nonempirical ab initio calculations. Chem. Rev. 99, 1999, 3247-3276.
  • Štefl R., Cheatham T. E, Špačková, N., Fadrná E., Berger I., Koča J., Šponer J.: Formation pathways of a guanine-quadruplex DNA revealed by molecular dynamics and thermodynamic analysis of the substates. Biophys. J. 85, 2003, 1787-1804.
  • Šponer J., Jurečka P., Hobza P.: Accurate interaction energies of hydrogen-bonded nucleic acid base pairs. J. Am. Chem. Soc. 126, 2004, 10142–10151.
  • Krasovska M. V., Sefcikova J., Špačková N., Šponer J., Walter N. G.: Structural dynamics of precursor and product of the RNA enzyme from the hepatitis delta virus as revealed by molecular dynamics simulations. J. Mol. Biol. 351, 2005, 731-748.
  • Rázga F., Koča J., Šponer J., Leontis N.B.: Hinge-like motions in RNA kink-turns: The role of the second A-minor motif and nominally unpaired bases. Biophys. J. 88, 2005, 3466-3485.
  • Computational studies of DNA and RNA. Šponer J., Lankaš F., Eds., Springer, 2006 

Biofyzikální ústav AV ČR »
Institute of Biophysics, AS CR »

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Reaction to the case of Tomáš Hudlický: Members of the Learned Society of the Czech Republic support the freedom of expression

„We believe that free exchange of ideas is a key condition for the pursuit of truth and that the honest opinions should be scrutinized, challenged or rebutted but not censored or suppressed,“ say 45 members of the Learned Society in a statement regarding the retracted opinion paper by Prof. Tomáš Hudlický.


The letter by Jan Konvalinka to the President and Vice-Chancellor of the Brock University regarding the retracted article of Prof. Tomáš Hudlický

Opinions could and should be challenged, questioned or refuted but never silenced. In order to be able to think, we have to have the right to inquire, question and even offend or be mistaken,” writes Assoc. Prof. Jan Konvalinka, a biochemist at the IOCB Prague and the Vice-Rector of the Charles University, to Gervan Fearon.


Prof Miroslav Bárta receives the Česká hlava National Government Award

Learned Society member, Prof. Mgr. Miroslav Bárta, Dr. (Charles University Faculty of Arts) received the Česká hlava (Czech Head) National Government Award on 25 November 2019. A renowned Czech Egyptologist and archaeologist, Professor Bárta researches the history of ancient civilisations, the human relationship to the natural environment, and also for many years the evolution of complex societies. He leads the Czech Institute of Egyptology for archaeological and environmental research in Egypt and Sudan. His principal research interest is the period of the pyramid builders of the Old Kingdom.