Calendar

No events are planned

Šponer Jiří

Prof., RNDr., DrSc.
Born March 2, 1964 in Brno

  • Molecular Biophysics and Computational Chemistry
  • Member of Learned Society since 2006

Educational and professional preparation:

  • 1987, Master degree (RNDr), Physics, Faculty of Science, Masaryk University, Brno 
  • 1992, CSc. (eq. PhD), Biophysics, Faculty of Science, Masaryk University, Brno 
  • 2001, DrSc. (Doctor of Science), Biophysics/Molecular Biology, Academy of Sciences of the Czech Republic

Employment and academic positions: 

  • 1988–1989, Scholarship, Masaryk University, Faculty of Science, Masaryk University, Brno (including one-year army service).
  • 1989–1992, Postgraduate student, Faculty of Medicine, Masaryk University, Brno.  
  • 1992, Scholarship, assistant professor, Masaryk University, Faculty of Science, Brno.
  • 1993, Junior researcher, Institute of Biohysics, Academy of Sciences of the Czech Republic, Brno 
  • 1994–2003, Researcher and Senior Research, J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague (part time 2001–2003).  
  • 2001-present: Senior Researcher and Head of Laboratory of Structure and Dynamics of Nucleic Acids, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno. 
  • 2004-present: (part time) Senior researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.

Membership in selected domestic scientific bodies:

  • Member of the Scientific Council of the Institute of Biophysics, AS CR, Brno. Since 2001

Notable awards:

  • 1999, Prize od the Learned Society of the Czech Republic for junior scientists
  • 2000, Prize of the Ministry of Education of the Czech Republic

Selected publications:

  • Šponer J., Hobza P.: Nonplanar geometries of DNA bases. Second order Moller-Plesset study. J. Phys. Chem. 98, 1994, 3161-3164.
  • Šponer J., Leszczynski J., Hobza P.: Structures and energies of hydrogen-bonded DNA base pairs. A nonempirical study with inclusion of electron correlation. J. Phys. Chem. 100, 1996, 1965-1974.
  • Šponer J., Leszczynski, J., Hobza P.: On the nature of nucleic acid base stacking. Nonempirical ab initio and empirical potential characterization of 10 stacked base pairs. Comparison of stacked and H-bonded base pairs. J. Phys. Chem. 100, 1996, 5590-5596.
  • Špacková N., Berger I., Šponer J.: Nanosecond molecular dynamics simulations of parallel and antiparallel guanine quadruplex molecules. J. Am. Chem. Soc. 121, 1999, 5519-5534.
  • Hobza P., Šponer J.: Structure, energetics, and dynamics of the nucleic acid base pairs: Nonempirical ab initio calculations. Chem. Rev. 99, 1999, 3247-3276.
  • Štefl R., Cheatham T. E, Špačková, N., Fadrná E., Berger I., Koča J., Šponer J.: Formation pathways of a guanine-quadruplex DNA revealed by molecular dynamics and thermodynamic analysis of the substates. Biophys. J. 85, 2003, 1787-1804.
  • Šponer J., Jurečka P., Hobza P.: Accurate interaction energies of hydrogen-bonded nucleic acid base pairs. J. Am. Chem. Soc. 126, 2004, 10142–10151.
  • Krasovska M. V., Sefcikova J., Špačková N., Šponer J., Walter N. G.: Structural dynamics of precursor and product of the RNA enzyme from the hepatitis delta virus as revealed by molecular dynamics simulations. J. Mol. Biol. 351, 2005, 731-748.
  • Rázga F., Koča J., Šponer J., Leontis N.B.: Hinge-like motions in RNA kink-turns: The role of the second A-minor motif and nominally unpaired bases. Biophys. J. 88, 2005, 3466-3485.
  • Computational studies of DNA and RNA. Šponer J., Lankaš F., Eds., Springer, 2006 

Biofyzikální ústav AV ČR »
Institute of Biophysics, AS CR »

Back to the list of articles

News

20.05.19

XXV. General Assembly of the Learned Society of the Czech Republic

The ceremonial part of the XXV. General Assembly of the Learned Society, at which the Medals of the Learned Society of the Czech Republic Societas Scientarium Bohemica Ad Laudem et Honorem and the awards of the Learned Society of the Czech Republic in the “Young Scientist” and “Grammar School Student” categories were presented, took place on Monday 20 May 2019 in the Great Hall of the Carolinum.

19.05.19

Bolzano lecture by prof. Kip S. Thorne

American physicist Kip S. Thorne, recipient of the Nobel Prize for 2017 for detection of gravitational waves, visited Prague at the invitation of he Learned Society. He held a series of “Bolzano lectures” and a lecture titled “Creating Gravitational-Wave Astronomy” for the Learned Society on 15 May 2019 in the Blue Auditorium of the Carolinum. The lecture was held with the support of the Karel Janeček Foundation and was received very enthusiastically.

07.05.19

XXV. General Assembly

The Czech Learned Society is holding its XXV. General Assembly on 20 and 21 May 2019. The Learned Society’s awards in the “Young Scientist” and “Grammar School Student” categories, Teaching Awards for pedagogic workers who promote interest in science and research at grammar schools and the Learned Society’s medals for meritorious contributions to the advance of science will be presented during a ceremony on 20 May at the Karolinum. Lectures by renowned scientists will also be presented. The second day will be reserved for the working part of the meeting, in the building of the Academy of Sciences of the Czech Republic.