No events are planned

Šponer Jiří

Prof., RNDr., DrSc.
Born March 2, 1964 in Brno

  • Molecular Biophysics and Computational Chemistry
  • Member of Learned Society since 2006

Educational and professional preparation:

  • 1987, Master degree (RNDr), Physics, Faculty of Science, Masaryk University, Brno 
  • 1992, CSc. (eq. PhD), Biophysics, Faculty of Science, Masaryk University, Brno 
  • 2001, DrSc. (Doctor of Science), Biophysics/Molecular Biology, Academy of Sciences of the Czech Republic

Employment and academic positions: 

  • 1988–1989, Scholarship, Masaryk University, Faculty of Science, Masaryk University, Brno (including one-year army service).
  • 1989–1992, Postgraduate student, Faculty of Medicine, Masaryk University, Brno.  
  • 1992, Scholarship, assistant professor, Masaryk University, Faculty of Science, Brno.
  • 1993, Junior researcher, Institute of Biohysics, Academy of Sciences of the Czech Republic, Brno 
  • 1994–2003, Researcher and Senior Research, J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Prague (part time 2001–2003).  
  • 2001-present: Senior Researcher and Head of Laboratory of Structure and Dynamics of Nucleic Acids, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno. 
  • 2004-present: (part time) Senior researcher, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.

Membership in selected domestic scientific bodies:

  • Member of the Scientific Council of the Institute of Biophysics, AS CR, Brno. Since 2001

Notable awards:

  • 1999, Prize od the Learned Society of the Czech Republic for junior scientists
  • 2000, Prize of the Ministry of Education of the Czech Republic

Selected publications:

  • Šponer J., Hobza P.: Nonplanar geometries of DNA bases. Second order Moller-Plesset study. J. Phys. Chem. 98, 1994, 3161-3164.
  • Šponer J., Leszczynski J., Hobza P.: Structures and energies of hydrogen-bonded DNA base pairs. A nonempirical study with inclusion of electron correlation. J. Phys. Chem. 100, 1996, 1965-1974.
  • Šponer J., Leszczynski, J., Hobza P.: On the nature of nucleic acid base stacking. Nonempirical ab initio and empirical potential characterization of 10 stacked base pairs. Comparison of stacked and H-bonded base pairs. J. Phys. Chem. 100, 1996, 5590-5596.
  • Špacková N., Berger I., Šponer J.: Nanosecond molecular dynamics simulations of parallel and antiparallel guanine quadruplex molecules. J. Am. Chem. Soc. 121, 1999, 5519-5534.
  • Hobza P., Šponer J.: Structure, energetics, and dynamics of the nucleic acid base pairs: Nonempirical ab initio calculations. Chem. Rev. 99, 1999, 3247-3276.
  • Štefl R., Cheatham T. E, Špačková, N., Fadrná E., Berger I., Koča J., Šponer J.: Formation pathways of a guanine-quadruplex DNA revealed by molecular dynamics and thermodynamic analysis of the substates. Biophys. J. 85, 2003, 1787-1804.
  • Šponer J., Jurečka P., Hobza P.: Accurate interaction energies of hydrogen-bonded nucleic acid base pairs. J. Am. Chem. Soc. 126, 2004, 10142–10151.
  • Krasovska M. V., Sefcikova J., Špačková N., Šponer J., Walter N. G.: Structural dynamics of precursor and product of the RNA enzyme from the hepatitis delta virus as revealed by molecular dynamics simulations. J. Mol. Biol. 351, 2005, 731-748.
  • Rázga F., Koča J., Šponer J., Leontis N.B.: Hinge-like motions in RNA kink-turns: The role of the second A-minor motif and nominally unpaired bases. Biophys. J. 88, 2005, 3466-3485.
  • Computational studies of DNA and RNA. Šponer J., Lankaš F., Eds., Springer, 2006 

Biofyzikální ústav AV ČR »
Institute of Biophysics, AS CR »

Back to the list of articles



Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.


The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.


The loss of Learned Society Fellow prof. Josef Koutecký

We regret to inform that prof. Josef Koutecký, a fellow of the Learned Society, a renowned physician and the founder of paediatric oncology in this country, passed away on 5 July 2019 at the age of 88. He founded paediatric oncology here in 1964 and a separate paediatric oncology department was then established at the Faculty Hospital in Motol, Prague in 1978.