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Forejt Jiří

Prof., MUDr., DrSc., DSc. 
Born on December 28, 1944

  • Molecular genetics and genomics of laboratory mice
  • Member of Learned Society since 1999

Educational and professional preparation

  • 1962-68, MUDr. Faculty of Medicine, Charles University, Hradec Králové;
  • 1975, CSc. in genetics, Institute of Molecular Genetics, CSAS, Prague;
  • 1991, DrSc. in genetics, Charles University, Prague;
  • 2002, Associate Professor, molecular biology and genetics, Faculty of Science CU
  • 2006, Full professor, molecular biology and genetics, Faculty of Science CU

Employment and academic positions

  • 1968-present, Institute of Molecular Genetics, AS CR (originally Institute of Experimental Biology and Genetics, CSAS);
  • 1980-present, Head, Department of Molecular Genetics (originally the Department of Developmental Genetics);
  • 1992-1993, 1995-1996, Visiting Professor, Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA

Membership in domestic scientific bodies

  • 2003-present, Chairman, Commission for Granting Title of DSc. in Genetics and Genomics
  • 2001-2005, Vice-Chairman, Council for Sciences AS CR

Membership and positions in selected international organizations and societies

  • 1984-1991, Elected member, Internat. Committee for Standardized Mouse Genetic Nomenclature
  • 1991-present, International Mammalian Genome Society
  • 1998-2001, Chairman, Chromosome 17 Committee
  • 1996-present, Howard Hughes Medical Institute–International Scholar
  • 1999-present, European Molecular Biology Organization-Elected member
  • 1998-present, Slovak Commissions for Defence of Doctoral Theses - 15-02-9, 15-01-9 and 15-16-9
  • 2003-2006, Member, EMBO YIP Selection Committee
  • 2003-2007, Elected member, Secretariat, International Mammalian Genome Society
  • 2008 –present, member, Scientific Advisory Board, Consortium of an Integrated Genome Research Network, Max-Planck-Institute for Molecular Genetics, Berlin
  • Member, editorial boards (in the past and present): Cytogenetics and Cell Genetics, Mouse Genome, Experimental and Clinical Immunogenetics, Roux Archives of Developmental Biology, Mammalian Genome, Folia Biologica.
    Ad hoc reviewer for: Proceedings of National Academy of Sciences USA, Genomics, Genes and Development, Genetical Research, Genome research, Genetics, J. Andrology, Gene.
  • Main organizer, international symposia: 1983, Molecular Biology of Embryonic and Teratocarcinoma Stem Cells; 1990, VIIth International Workshop of Mouse Molecular Genetics; 1996, Howard Hughes Medical Institute Conference of International Fellows- (Chairman, local organization committee), 22nd International Mouse Genome Conference, Prague, 2008.

Notable awards

  • 1984, Prize, CSAS
  • 1999, 2009, Prize, AS CR
  • 2004, Gregor Mendel Medal, AS CR
  • 2007-2013, Praemium Academiae, AS CR
  • 2009, Prize, Ministry of Education, Youth and Sports

Selected publications

  • Forejt, J.: Spermatogenic failure of translocation heterozygotes affected by H-2 linked gene in mouse. Nature (London) 260,143-145, 1976
  • Forejt, J.: X-inactivation and its role in male sterility. In: Chromosomes Today, Vol. 8 (A.Gropp, M. D.Bennett and U. Wolf, Eds.) George Allen and Unwin, Hemel Hempstead (England) 1984, p.117-127
  • Forejt, J., Gregorova, S., Dohnal, K., Nosek, J.: Gene expression of differentiated parent in teratocarcinoma cell hybrids. Repression or reprogramming? Cell Differ. 15, 129-134, 1984.
  • Kralova, J., Jansa, P., Forejt, J.: A novel downstream regulatory element of the mouse H-2K b class I major histocompatibility gene. EMBO J. 11, 4591-4600,1992
  • Forejt, J., Gregorova, S.: Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus. Cell 70, 443-450, 1992
  • Forejt, J.: Hybrid sterility in the mouse. Trend. Genet. 12, 412-417, 1996
  • Forejt, J.: Nondisjuction. In: Encyclopedia of Genetics. S. Brenner and J. Miller, Eds. Academic Press, London New York, 2001, pp. 1345-1347
  • Divina, P., Forejt, J.: The mouse SAGE site: database of public mouse SAGE libraries. Nucl. Acid. Res. 32, D482-D483, 2004
  • Homolka, D., Ivanek, R., Capkova, J., Jansa, P., Forejt, J.: Chromosomal rearrangement interferes with meiotic X-chromosome inactivation. Genome Research 17, 1431-1437, 2007
  • Gregorová, S., Divina, P., Storchova, R., Trachtulec, Z., Fotopulosova, V., Svenson, K.L., Donahue, L.R., Paigen, B., Forejt, J.: Mouse consomic strains: Exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Research 18, 509-505, 2008.
  • Mihola, O., Trachtulec, Z., Vlcek, C., Schimenti, J.C., Forejt, J: A mouse speciation gene encodes a meiotic Histone H3 methyltransferase. Science 323, 373—375, 2009

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News

25.07.19

Luboš Perek is celebrating his 100th year

Founding fellow of the Learned Society and its doyen, astronomer doc. RNDr. Luboš Perek, DrSc, is celebrating his 100th birthday on 26 July 2019. He is an indelible part of history as the person who helped define cosmic space, he was the first to point out the issue of cosmic waste and was also a teacher to the most important Czechoslovak astronomers. Let us express our respect and admiration of the extraordinary scientific career of a person who worked tirelessly and continues to work. The Learned Society wishes Mr Perek health, optimism and joy in the oncoming years.

23.07.19

The Academy of Sciences of the Czech Republic has appealed to the Hungarian President to support academic freedom

On Friday 19 July the Academy of Sciences of the Czech Republic and the Learned Society of the Czech Republic sent a letter to Hungarian President János Ánder, in which they state their concerns regarding the situation in respect to management and funding of scientific activities in Hungary. An act, according to which not the Academy of Sciences, but a thirteen-member political committee, will decide on research, funding of scientific activities and establishment or closure of scientific workplaces, will come into force on 1 September.

07.07.19

The loss of Learned Society Fellow prof. Josef Koutecký

We regret to inform that prof. Josef Koutecký, a fellow of the Learned Society, a renowned physician and the founder of paediatric oncology in this country, passed away on 5 July 2019 at the age of 88. He founded paediatric oncology here in 1964 and a separate paediatric oncology department was then established at the Faculty Hospital in Motol, Prague in 1978.