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Vojtěšek Bořivoj

RNDr., DrSc.
Born October 25, 1960

  • Molecular oncology
  • Member of Learned Society since 2003

Educational and professional preparation:

  • 1976-1979, graduate, academic secondary school, Břeclav;
  • 1979-1984, Faculty of Natural Science, Department of Molecular Biology, Jan Evangelista Purkyně University, Brno;
  • 1985, RNDr.; 1990 CSc.;
  • 1996, DrSc., scientific field of oncology, Academy of Sciences of Czech Republic (AC CR), Prague and Slovak Academy of Sciences Bratislava.

Employment and academic positions:

  • 1985-present, Masaryk Memorial Cancer Institute (MMCI), Brno (formerly the Research Institute of Clinical and Experimental Oncology);
  • 1985-1999, principal scientist, MMCI;
  • 1999-2000, Head, Department of Cellular and Molecular Oncology, MMCI;
  • 2001-present, Head, working group, Biology of Tumours and Proteomics, MMCI

Membership in selected domestic scientific bodies:

  • 1993-present, member, Scientific Council, MMCI
  • 1999-2002, member, Scientific Council, Second Faculty of Medicine, Charles University (FM CU), Prague
  • 2003-present, member, Scientific Council, Faculty of Science, Palacký University, Olomouc
  • 2003-present, member, Scientific Council of Biophysical Institute, AS CR, Brno
  • 2003-present, member, Scientific Council, Institute of Animal Physiology, AS CR, Liběchov

Membership and positions in international organizations and societies:

  • Member, European Association for Cancer Research (EACR)

Notable awards:

  • 1996, Award, Minister of Health, Ministry of Health
  • 1999, Award, Minister of Health, Ministry of Health
  • 2001, Award, Minister of Health, Ministry of Health
  • 2003, Award, Minister of Health, Ministry of Health

Selected publications:

  • B. Vojtesek, J. Bartek, C. A. Midgley, D. P. Lane: An immunochemical analysis of human p53: New monoclonal antibodies and epitope mapping using recombinant p53. J. Immunol. Methods 151, 237-244 (1992)
  • B. Vojtesek, D. P. Lane: Regulation of p53 protein expression in human breast cancer cell lines. J. Cell Science 105, 607-612 (1993)
  • B. Vojtesek, C. J. Fisher, D. M. Barnes, D. P. Lane: Comparison between p53 staining in tissue sections and p53 proteins levels measured by an ELISA technique. Br. J. Cancer 67, 1254-1258 (1993)
  • K. H. Vousden, B. Vojtesek, CH. Fisher, D. P. Lane: HPV-16E7 or adenovirus E1A can overcome the growth arrest of cells immortalized with a temperature-sensitive p53. Oncogene 8, 1697-1702 (1993)
  • B. Vojtesek, H. Dolezalova, L. Lauerova, M. Svitakova, P. Havliš, J. Kovarik, C. A. Midgley, D. P. Lane: Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein. Oncogene 10, 389-393 (1995)
  • D. Niewolik, B. Vojtesek, J. Kovarik: p53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence. Oncogene 10 , 881-890 (1995)
  • V. Kotala, S. Uldrijan, M. Horký, M. Trbůšek, M. Strnad, B. Vojtěšek: Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases. Cell. Mol. Life. Sci. 9, 1333-13339 (2001)
  • R. Nenutil, P. Ceskova, P. J. Coates, K. Nylander, B. Vojtesek: Differential Expression of p73alpha in Normal Ectocervical Epithelium, Cervical Intraepithelial Neoplasia, and Invasive Squamous Cell Carcinoma. Int. J. Gynecol Pathol. 22(4), 386-392 (2003)
  • M.A. Sheard, S. Uldrijan, B. Vojtesek.: Role of p53 in regulating constitutive and X-radiation-inducible CD95 expression and function in carcinoma cells. Cancer Res. 63(21), 7176-7184 (2003)
  • S. Pospisilova, V. Brazda, K. Kucharikova, M.G. Luciani, T.R. Hupp, P. Skladal, E. Palecek, B. Vojtesek: Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2. Biochem J. 378 (Pt 3), 939-947 (2004)

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News

26.06.20

Reaction to the case of Tomáš Hudlický: Members of the Learned Society of the Czech Republic support the freedom of expression

„We believe that free exchange of ideas is a key condition for the pursuit of truth and that the honest opinions should be scrutinized, challenged or rebutted but not censored or suppressed,“ say 45 members of the Learned Society in a statement regarding the retracted opinion paper by Prof. Tomáš Hudlický.

24.06.20

The letter by Jan Konvalinka to the President and Vice-Chancellor of the Brock University regarding the retracted article of Prof. Tomáš Hudlický

Opinions could and should be challenged, questioned or refuted but never silenced. In order to be able to think, we have to have the right to inquire, question and even offend or be mistaken,” writes Assoc. Prof. Jan Konvalinka, a biochemist at the IOCB Prague and the Vice-Rector of the Charles University, to Gervan Fearon.

27.11.19

Prof Miroslav Bárta receives the Česká hlava National Government Award

Learned Society member, Prof. Mgr. Miroslav Bárta, Dr. (Charles University Faculty of Arts) received the Česká hlava (Czech Head) National Government Award on 25 November 2019. A renowned Czech Egyptologist and archaeologist, Professor Bárta researches the history of ancient civilisations, the human relationship to the natural environment, and also for many years the evolution of complex societies. He leads the Czech Institute of Egyptology for archaeological and environmental research in Egypt and Sudan. His principal research interest is the period of the pyramid builders of the Old Kingdom.