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• Forejt Jiří

Assoc. Prof., MUDr., DrSc.
Born on December 28, 1944

• Mammalian genetics and genomics of laboratory mice
• Member of Learned Society since 1999

Educational and professional preparation:

• 1962-68, MUDr. Faculty of Medicine, Charles University, Hradec Králové;
• 1975, CSc. in genetics, Institute of Molecular Genetics, CSAS, Prague;
• 1991, DrSc. in genetics, Charles University, Prague;
• 2002, Associate Professor, molecular biology and genetics, Faculty of Science CU

Employment and academic positions:

• 1968-present, Institute of Molecular Genetics, AS CR (originally Institute of Experimental Biology and Genetics, CSAS);
• 1980-present, Head, Department of Molecular Genetics (originally the Department of Developmental Genetics);
• 1992-1993, Visiting Professor, Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA

Membership in domestic scientific bodies:

• 2003-present, Chairman, Commission for Granting Title of DSc. in Genetics and Genomics
• 2001-present, Vice-Chairman, Council for Sciences AS CR

Membership and positions in selected international organizations and societies:

• 1984-1991, Elected member, Internat. Committee for Standardized Mouse Genetic Nomenclature
• 1991-present, International Mammalian Genome Society
• 1998-2001, Chairman, Chromosome 17 Committee
• 1996-present, Howard Hughes Medical Institute–International Scholar
• 1999-present, European Molecular Biology Organization-Elected member
• 1998-present, Slovak Commissions for Defence of Doctoral Theses - 15-02-9, 15-01-9 and 15-16-9
• 2003-2006, Member, EMBO YIP Selection Committee
• 2003-2007, Elected member, Secretariat, International Mammalian Genome Society
• Member, editorial boards (in the past and present): Cytogenetics and Cell Genetics, Mouse Genome, Experimental and Clinical Immunogenetics, Roux Archives of Developmental Biology, Mammalian Genome, Folia Biologica. Ad hoc reviewer for: Proceedings of National Academy of Sciences USA, Genomics, Genes and Development, Genetical Research, Genome research, Genetics, J. Andrology, Gene.
• Main organizer, international symposia: 1983, Molecular Biology of Embryonic and Teratocarcinoma Stem Cells; 1990, VIIth International Workshop of Mouse Molecular Genetics; 1996, Howard Hughes Medical Institute Conference of International Fellows- (Chairman, local organization committee)

Notable awards:

• 1984, Prize, CSAS
• 1999, Prize, AS CR

Selected publications:

• Forejt, J.: Spermatogenic failure of translocation heterozygotes affected by H-2 linked gene in mouse. Nature (London) 260,143-145, 1976
• Forejt, J.: X-inactivation and its role in male sterility. In: Chromosomes Today, Vol. 8 (A.Gropp, M. D.Bennett and U. Wolf, Eds.) George Allen and Unwin, Hemel Hempstead (England) 1984, p.117-127
• Forejt, J., Gregorova, S., Dohnal, K., Nosek, J.: Gene expression of differentiated parent in teratocarcinoma cell hybrids. Repression or reprogramming? Cell Differ. 15,129-134, 1984.
• Kralova, J., Jansa, P., Forejt, J.: A novel downstream regulatory element of the mouse H-2K b class I major histocompatibility gene. EMBO J. 11, 4591-4600,1992
• Forejt, J., Gregorova, S.: Genetic analysis of genomic imprinting: An Imprintor-1 gene controls inactivation of the paternal copy of the mouse Tme locus. Cell 70, 443-450, 1992
• Forejt, J.: Hybrid sterility in the mouse. Trend. Genet. 12, 412-417, 1996
• Forejt, J., Saam, J.R., Gregorova, S., Tilghman, S.M.: Monoallelic expression of reactivated imprinted genes in embryonal carcinoma cell hybrids. Exp. Cell Res. 252, 416-422, 1999.
• Forejt, J.: Nondisjuction. In: Encyclopedia of Genetics. S. Brenner and J. Miller, Eds. Academic Press, London New York, 2001, pp. 1345-1347
• Vacik, T, Forejt, J.: Quantification of expression and methylation of the Igf2r imprinted gene in segmental trisomic mouse model. Genomics, 82, 261-268, 2003
• Divina, P., Forejt, J.: The mouse SAGE site: database of public mouse SAGE libraries. Nucl. Acid. Res. 32, D482-D483, 2004

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